An evaluation in vitro of the efficacy of nutlin-3 and topotecan in combination with (177)Lu-DOTATATE for the treatment of neuroblastoma

Targeted radiotherapy of metastatic neuroblastoma using the somatostatin receptor (SSTR)-targeted octreotide analogue DOTATATE radiolabelled with lutetium-177 ((177)Lu-DOTATATE) is a promising strategy. This study evaluates whether its effectiveness may be enhanced by combination with radiosensitisi...

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Detalles Bibliográficos
Autores principales: Tesson, Mathias, Vasan, Richa, Hock, Andreas, Nixon, Colin, Rae, Colin, Gaze, Mark, Mairs, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044389/
https://www.ncbi.nlm.nih.gov/pubmed/30018737
http://dx.doi.org/10.18632/oncotarget.25607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044389/
https://www.ncbi.nlm.nih.gov/pubmed/30018737
http://dx.doi.org/10.18632/oncotarget.25607

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