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Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism
[Image: see text] Aldehyde oxidase (AO) is a molybdenum-containing enzyme involved in the clearance of drug compounds containing aldehydes and N-containing heterocyclic fragments. AO has gained considerable interest in recent years because of examples of too fast clearance of drug compounds in devel...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044498/ https://www.ncbi.nlm.nih.gov/pubmed/30023718 http://dx.doi.org/10.1021/acsomega.7b00658 |