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A Short-Length Peptide YY Analogue with Anorectic Effect in Mice

[Image: see text] Peripheral administration of PYY(3–36), a fragment of peptide YY (PYY), has been reported to reduce food intake by activating the neuropeptide Y2 receptor (Y2R). An N-terminally truncated PYY analogue, benzoyl-[Ala(26),Ile(28,31)]PYY(25–36) (1), showed a relatively potent agonist a...

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Detalles Bibliográficos
Autores principales: Nishizawa, Naoki, Niida, Ayumu, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Hirabayashi, Hideki, Amano, Nobuyuki, Ohtaki, Tetsuya, Asami, Taiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044503/
https://www.ncbi.nlm.nih.gov/pubmed/30023658
http://dx.doi.org/10.1021/acsomega.7b00258