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A dual regulation mechanism of histidine kinase CheA identified by combining network-dynamics modeling and system-level input-output data
It is challenging to decipher molecular mechanisms in biological systems from system-level input-output data, especially for complex processes that involve interactions among multiple components. We addressed this general problem for the bacterial histidine kinase CheA, the activity of which is regu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044545/ https://www.ncbi.nlm.nih.gov/pubmed/29965962 http://dx.doi.org/10.1371/journal.pcbi.1006305 |