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Azide–Alkyne Cycloaddition En Route to 1H-1,2,3-Triazole-Tethered Isatin–Ferrocene, Ferrocenylmethoxy–Isatin, and Isatin–Ferrocenylchalcone Conjugates: Synthesis and Antiproliferative Evaluation
[Image: see text] Diverse series of isatin–ferrocene conjugates were synthesized via Cu-promoted azide–alkyne cycloaddition reaction with an aim of probing their antiproliferative structure–activity relationship against MCF-7 (estrogen receptor positive) and MDA-MB-231 (triple negative) cell lines....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044575/ https://www.ncbi.nlm.nih.gov/pubmed/30023800 http://dx.doi.org/10.1021/acsomega.7b01755 |