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Azide–Alkyne Cycloaddition En Route to 1H-1,2,3-Triazole-Tethered Isatin–Ferrocene, Ferrocenylmethoxy–Isatin, and Isatin–Ferrocenylchalcone Conjugates: Synthesis and Antiproliferative Evaluation

[Image: see text] Diverse series of isatin–ferrocene conjugates were synthesized via Cu-promoted azide–alkyne cycloaddition reaction with an aim of probing their antiproliferative structure–activity relationship against MCF-7 (estrogen receptor positive) and MDA-MB-231 (triple negative) cell lines....

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Detalles Bibliográficos
Autores principales: Singh, Amandeep, Saha, Sourav Taru, Perumal, Shanen, Kaur, Mandeep, Kumar, Vipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044575/
https://www.ncbi.nlm.nih.gov/pubmed/30023800
http://dx.doi.org/10.1021/acsomega.7b01755