Comparative Study of 5′- and 3′-Linked CpG–Antigen Conjugates for the Induction of Cellular Immune Responses

[Image: see text] Conjugation of CpG to an antigen induces a stronger immune response compared to that of the mixture. This study compares the in vitro immunostimulatory activity of CpG conjugated via either its 5′ or 3′ end to the model antigen ovalbumin (OVA). CpG modified with an amine at either...

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Detalles Bibliográficos
Autores principales: Kramer, Katrin, Young, Sarah L., Walker, Greg F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044624/
https://www.ncbi.nlm.nih.gov/pubmed/30023513
http://dx.doi.org/10.1021/acsomega.6b00368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044624/
https://www.ncbi.nlm.nih.gov/pubmed/30023513
http://dx.doi.org/10.1021/acsomega.6b00368

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