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Denaturation of dsDNA Induced by Specific Major Groove Binding of Cadmium Ion to Thymine
[Image: see text] The toxicity of cadmium causes varying degrees of risk to organisms. The underlying mechanism has been conventionally attributed to Cd(2+)-ion-induced oxidative stress. Here, we propose that the Cd(2+) ion directly and stably binds with the thymine specifically in the major groove...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044676/ https://www.ncbi.nlm.nih.gov/pubmed/30023584 http://dx.doi.org/10.1021/acsomega.7b01377 |