Counterpointing Scenarios on the Fate of Different Prototropic Forms of Norfloxacin Housed in the Pocket of Lysozyme: The Nonelectrostatic Interactions in the Protein Interior Are in the Controlling Role on the Prototropic Equilibria of the Guest

[Image: see text] Herein, we report a comprehensive study on the interaction of three protomeric forms of the antibacterial drug norfloxacin (nfx) with the enzymatic protein human lysozyme (lyz). Norfloxacin, having the option for two-stage acid–base equilibria, converts from cationic (nfx(+)) to zw...

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Detalles Bibliográficos
Autores principales: Das, Ishita, Halder, Mintu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044686/
https://www.ncbi.nlm.nih.gov/pubmed/30023748
http://dx.doi.org/10.1021/acsomega.7b00703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044686/
https://www.ncbi.nlm.nih.gov/pubmed/30023748
http://dx.doi.org/10.1021/acsomega.7b00703

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