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Small-Molecule Ice Recrystallization Inhibitors Improve the Post-Thaw Function of Hematopoietic Stem and Progenitor Cells

[Image: see text] The success of hematopoietic stem cell transplantation depends in part on the number and the quality of cells transplanted. Cryoinjuries during freezing and thawing reduce the ability of hematopoietic stem and progenitor cells (HSPCs) to proliferate and differentiate after thawing....

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Detalles Bibliográficos
Autores principales: Briard, Jennie G., Jahan, Suria, Chandran, Priya, Allan, David, Pineault, Nicolas, Ben, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044699/
https://www.ncbi.nlm.nih.gov/pubmed/30023498
http://dx.doi.org/10.1021/acsomega.6b00178