Cargando…

Lysine Scanning of Arg(10)–Teixobactin: Deciphering the Role of Hydrophobic and Hydrophilic Residues

[Image: see text] Teixobactin is a recently discovered antimicrobial cyclodepsipeptide with good activity against Gram positive bacteria. Taking Arg(10)–teixobactin as a reference, where the nonproteinogenic residue l-allo-enduracididine was substituted by arginine, a lysine scan was performed to id...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdel Monaim, Shimaa A. H., Jad, Yahya E., Ramchuran, Estelle J., El-Faham, Ayman, Govender, Thavendran, Kruger, Hendrik G., de la Torre, Beatriz G., Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044708/
https://www.ncbi.nlm.nih.gov/pubmed/30023506
http://dx.doi.org/10.1021/acsomega.6b00354