Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors

[Image: see text] Antibody–drug conjugates (ADCs) are a new class of anticancer therapeutics that combine the selectivity of targeted treatment, ensured by monoclonal antibodies, with the potency of the cytotoxic agent. Here, we applied an analogous approach, but instead of an antibody, we used fibr...

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Detalles Bibliográficos
Autores principales: Krzyscik, Mateusz Adam, Zakrzewska, Malgorzata, Sørensen, Vigdis, Sokolowska-Wedzina, Aleksandra, Lobocki, Michal, Swiderska, Karolina Weronika, Krowarsch, Daniel, Wiedlocha, Antoni, Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044718/
https://www.ncbi.nlm.nih.gov/pubmed/30023704
http://dx.doi.org/10.1021/acsomega.7b00116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044718/
https://www.ncbi.nlm.nih.gov/pubmed/30023704
http://dx.doi.org/10.1021/acsomega.7b00116

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