Design and Synthesis of Aza-/Oxa Heterocycle-Based Conjugates as Novel Anti-Inflammatory Agents Targeting Cyclooxygenase-2

[Image: see text] A library of hybrid molecules was procured by the combination of triazine–indole adduct with morpholine/piperidine/pyrrolidine and pyrazole/pyrimidine/oxindole moieties. Enzyme immunoassays on cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) identified compound 6 having an IC(...

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Detalles Bibliográficos
Autores principales: Kaur, Sukhmeet, Kumari, Priya, Singh, Gurjit, Bhatti, Rajbir, Singh, Palwinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044720/
https://www.ncbi.nlm.nih.gov/pubmed/30023927
http://dx.doi.org/10.1021/acsomega.8b00445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044720/
https://www.ncbi.nlm.nih.gov/pubmed/30023927
http://dx.doi.org/10.1021/acsomega.8b00445

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