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Development of Escherichia coli Asparaginase II for Immunosensing: A Trade-Off between Receptor Density and Sensing Efficiency

[Image: see text] The clinical success of Escherichia colil-asparaginase II (EcAII) as a front line chemotherapeutic agent for acute lymphoblastic leukemia (ALL) is often compromised because of its silent inactivation by neutralizing antibodies. Timely detection of silent immune response can rely on...

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Detalles Bibliográficos
Autores principales: Charbonneau, David M., Aubé, Alexandra, Rachel, Natalie M., Guerrero, Vanessa, Delorme, Kevin, Breault-Turcot, Julien, Masson, Jean-François, Pelletier, Joelle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044767/
https://www.ncbi.nlm.nih.gov/pubmed/30023654
http://dx.doi.org/10.1021/acsomega.7b00110