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Seed-Induced Heterogeneous Cross-Seeding Self-Assembly of Human and Rat Islet Polypeptides

[Image: see text] Amyloid peptides can misfold and aggregate into amyloid oligomers and fibrils containing conformationally similar β-sheet structures, which are linked to the pathological hallmark of many neurodegenerative diseases. These β-sheet-rich amyloid aggregates provide common structural mo...

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Detalles Bibliográficos
Autores principales: Hu, Rundong, Ren, Baiping, Zhang, Mingzhen, Chen, Hong, Liu, Yonglan, Liu, Lingyun, Gong, Xiong, Jiang, Binbo, Ma, Jie, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044775/
https://www.ncbi.nlm.nih.gov/pubmed/30023616
http://dx.doi.org/10.1021/acsomega.6b00559