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Investigation of Core Structure and Stability of Human Pyruvate Dehydrogenase Complex: A Coarse-Grained Approach

[Image: see text] The human pyruvate dehydrogenase complex (hPDC) is a large macromolecular machine, and its unique structural and functional properties make it a versatile target for manipulation aiming for the design of new types of artificial multienzyme cascades. However, model-based and hence s...

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Detalles Bibliográficos
Autores principales: Hezaveh, Samira, Zeng, An-Ping, Jandt, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044784/
https://www.ncbi.nlm.nih.gov/pubmed/30023628
http://dx.doi.org/10.1021/acsomega.6b00386