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Ligand Selectivity between the ADP-Ribosylating Toxins: An Inverse-Docking Study for Multitarget Drug Discovery

[Image: see text] Bacterial adenosine 5’-diphosphate-ribosylating toxins are encoded by several human pathogens, such as Pseudomonas aeruginosa (exotoxin A (ETA)), Corynebacterium diphtheriae (diphtheria toxin (DT)), and Vibrio cholerae (cholix toxin (CT)). The toxins modify eukaryotic elongation fa...

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Detalles Bibliográficos
Autores principales: Saenz-Méndez, Patricia, Eriksson, Martin, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044789/
https://www.ncbi.nlm.nih.gov/pubmed/30023642
http://dx.doi.org/10.1021/acsomega.7b00010