Enabling Biocatalysis by High-Throughput Protein Engineering Using Droplet Microfluidics Coupled to Mass Spectrometry

[Image: see text] Directed Evolution is a key technology driving the utility of biocatalysis in pharmaceutical synthesis. Conventional approaches to Directed Evolution are conducted using bacterial cells expressing enzymes in microplates, with catalyzed reactions measured by HPLC, high-performance l...

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Detalles Bibliográficos
Autores principales: Diefenbach, Xue W., Farasat, Iman, Guetschow, Erik D., Welch, Christopher J., Kennedy, Robert T., Sun, Shuwen, Moore, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044804/
https://www.ncbi.nlm.nih.gov/pubmed/30023807
http://dx.doi.org/10.1021/acsomega.7b01973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044804/
https://www.ncbi.nlm.nih.gov/pubmed/30023807
http://dx.doi.org/10.1021/acsomega.7b01973

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