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Encapsulation and Enhanced Delivery of Topoisomerase I Inhibitors in Functionalized Carbon Nanotubes

[Image: see text] The topoisomerase I inhibitors SN-38 and camptothecin (CPT) have shown potent anticancer activity, but water insolubility and metabolic instability limits their clinical application. Utilizing carbon nanotubes as a protective shell for water-insoluble SN-38 and CPT while maintainin...

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Detalles Bibliográficos
Autores principales: Chae, Sieun, Kim, Dahee, Lee, Kyung-jin, Lee, Dasol, Kim, Young-O, Jung, Yong Chae, Rhee, Sang Dal, Kim, Kwang Rok, Lee, Jeong-O, Ahn, Sunjoo, Koh, Byumseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044808/
https://www.ncbi.nlm.nih.gov/pubmed/30023933
http://dx.doi.org/10.1021/acsomega.8b00399