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Highly Selective and Tunable Protein Hydrolysis by a Polyoxometalate Complex in Surfactant Solutions: A Step toward the Development of Artificial Metalloproteases for Membrane Proteins

[Image: see text] This study represents the first example of protein hydrolysis at pH = 7.4 and 60 °C by a metal-substituted polyoxometalate (POM) in the presence of a zwitterionic surfactant. Edman degradation results show that in the presence of 0.5% w/v 3-[(3-cholamidopropyl)dimethylammonio]-1-pr...

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Detalles Bibliográficos
Autores principales: Sap, Annelies, Vandebroek, Laurens, Goovaerts, Vincent, Martens, Erik, Proost, Paul, Parac-Vogt, Tatjana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044816/
https://www.ncbi.nlm.nih.gov/pubmed/30023653
http://dx.doi.org/10.1021/acsomega.7b00168