Cargando…

FD5180, a Novel Protein Kinase Affinity Probe, and the Effect of Bead Loading on Protein Kinase Identification

[Image: see text] The effects of compound loading on the identification of protein kinases (PKs) was examined using two previously reported sepharose-supported PK inhibitors (PKIs): bisindolylmaleimide X (S1) and CZC8004 (S2). Compound loadings of 0.1, 0.5, 2.5, 5, 10, 25, and 50% content and an eth...

Descripción completa

Detalles Bibliográficos
Autores principales: Deane, Fiona M., Lin, Andrew J. S., Hains, Peter G., Pilgrim, Sarah L., Robinson, Phillip J., McCluskey, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044883/
https://www.ncbi.nlm.nih.gov/pubmed/30023706
http://dx.doi.org/10.1021/acsomega.7b00020