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Substituent, Charge, and Size Effects on the Fluorogenic Performance of Amyloid Ligands: A Small-Library Screening Study

[Image: see text] Developing new molecular ligands for the direct detection and tracking of amyloid protein aggregates is key to understanding and defeating myriad neurodegenerative and other disorders including Alzheimer’s and Parkinson’s diseases. A crucial factor in the performance of an amyloid...

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Detalles Bibliográficos
Autores principales: Donabedian, Patrick L., Evanoff, Mallory, Monge, Florencia A., Whitten, David G., Chi, Eva Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044928/
https://www.ncbi.nlm.nih.gov/pubmed/30023689
http://dx.doi.org/10.1021/acsomega.7b00231