Mutational Analysis of a Conserved Glutamate Reveals Unique Mechanistic and Structural Features of the Phosphatase PRL-3

[Image: see text] Phosphatase of regenerating liver (PRL)-3 (PTP4A3) has gained much attention in cancer research due to its involvement in tumor promoting and metastatic processes. It belongs to the protein tyrosine phosphatase (PTP) superfamily and is thought to follow the catalytic mechanism shar...

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Detalles Bibliográficos
Autores principales: Hoeger, Birgit, Rios, Pablo, Berteotti, Anna, Hoermann, Bernhard, Duan, Guangyou, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044973/
https://www.ncbi.nlm.nih.gov/pubmed/30023603
http://dx.doi.org/10.1021/acsomega.7b01208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044973/
https://www.ncbi.nlm.nih.gov/pubmed/30023603
http://dx.doi.org/10.1021/acsomega.7b01208

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