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Intracellular Delivery of β-Galactosidase Enzyme Using Arginase-Responsive Dextran Sulfate/Poly-l-arginine Capsule for Lysosomal Storage Disorder

[Image: see text] β-Galactosidase (β-gal) is one of the important lysosomal enzymes that is involved in the breakdown of glycosphingolipids (e.g., GM1 ganglioside), and its deficiency leads to GM1 Gangliosidosis, a lysosomal storage disorder (LSD). Intracellular delivery of β-gal is one of the prefe...

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Detalles Bibliográficos
Autores principales: Gupta, Meenakshi, Pandey, Himanshu, Sivakumar, Sri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044979/
https://www.ncbi.nlm.nih.gov/pubmed/30023598
http://dx.doi.org/10.1021/acsomega.7b01230