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Network of Conformational Transitions Revealed by Molecular Dynamics Simulations of the Carbonic Anhydrase II Apo-Enzyme
[Image: see text] Human carbonic anhydrase II (HCA II) is an enzyme that catalyzes the reversible hydration of CO(2) into bicarbonate (HCO(3)(–)) and a proton (H(+)) as well as other reactions at an extremely high rate. This enzyme plays fundamental roles in human physiology/pathology, such as contr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045336/ https://www.ncbi.nlm.nih.gov/pubmed/30023582 http://dx.doi.org/10.1021/acsomega.7b01414 |