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Network of Conformational Transitions Revealed by Molecular Dynamics Simulations of the Carbonic Anhydrase II Apo-Enzyme

[Image: see text] Human carbonic anhydrase II (HCA II) is an enzyme that catalyzes the reversible hydration of CO(2) into bicarbonate (HCO(3)(–)) and a proton (H(+)) as well as other reactions at an extremely high rate. This enzyme plays fundamental roles in human physiology/pathology, such as contr...

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Detalles Bibliográficos
Autores principales:	Ma, Huishu, Li, Anbang, Gao, Kaifu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045336/ https://www.ncbi.nlm.nih.gov/pubmed/30023582 http://dx.doi.org/10.1021/acsomega.7b01414

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