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On the Mechanism of Action of Dragmacidins I and J, Two New Representatives of a New Class of Protein Phosphatase 1 and 2A Inhibitors

[Image: see text] Two new brominated bis(indole) alkaloids, dragmacidins I (1) and J (2), showing low micromolar cytostatic activity, along with three known congeners were isolated from the Tanzanian sponge Dragmacidon sp. and their structures determined by the analysis of their NMR and MS data. Fro...

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Detalles Bibliográficos
Autores principales: Cruz, Patricia G., Martínez Leal, Juan Fernando, Daranas, Antonio Hernández, Pérez, Marta, Cuevas, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045348/
https://www.ncbi.nlm.nih.gov/pubmed/30023878
http://dx.doi.org/10.1021/acsomega.7b01786