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Optimization of Formulations Consisting of Layered Double Hydroxide Nanoparticles and Small Interfering RNA for Efficient Knockdown of the Target Gene

[Image: see text] Layered double hydroxide (LDH) nanoparticles (NPs) are safe and effective vectors for small interfering RNA (siRNA) delivery. However, it is unclear whether there are optimal parameters for the efficient delivery of functional siRNA using LDH NPs. In this research, we comprehensive...

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Detalles Bibliográficos
Autores principales: Wu, Yanheng, Gu, Wenyi, Chen, Chen, Do, Son Trong, Xu, Zhi Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045353/
https://www.ncbi.nlm.nih.gov/pubmed/30023905
http://dx.doi.org/10.1021/acsomega.8b00397