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Recognition Site Generated by Natural Changes in Erm Proteins Leads to Unexpectedly High Susceptibility to Chymotrypsin

[Image: see text] Erms are proteins that methylate the adenine (A2058) in Escherichia coli 23S rRNA, which results in resistance to macrolide, lincosamide, and streptogramin B antibiotics. In a previous report, ErmN appeared to be more susceptible to contaminating proteases in DNase I. To determine...

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Detalles Bibliográficos
Autores principales: Le, Tien, Lee, Hak Jin, Jin, Hyung Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045372/
https://www.ncbi.nlm.nih.gov/pubmed/30023575
http://dx.doi.org/10.1021/acsomega.7b00446