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Radiolabeling and Preclinical Evaluation of a New S-Alkylated Cysteine Derivative Conjugated to C-Substituted Macrocycle for Positron Emission Tomography

[Image: see text] A new S-alkylated cysteine-derivatized tumor targeting agent, 2,2′-(12-(2-((2-acetamido-2-carboxyethyl)thio)acetamido)-11,13-dioxo-1,4,7,10-tetraazacyclotridecane-4,7-diyl)diacetic acid was developed for positron emission tomography (PET) imaging. N-Acetyl cysteine (NAC) was conjug...

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Detalles Bibliográficos
Autores principales: Prakash, Surbhi, Hazari, Puja Panwar, Meena, Virendra Kumar, Mishra, Anil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045381/
https://www.ncbi.nlm.nih.gov/pubmed/30023950
http://dx.doi.org/10.1021/acsomega.8b00059