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Small-Molecule Ligands as Potential GDNF Family Receptor Agonists
[Image: see text] To find out potential GDNF family receptor α1 (GFRα1) agonists, small molecules were built up by molecular fragments according to the structure-based drug design approach. Molecular docking was used to identify their binding modes to the biological target GFRα1 in GDNF-binding pock...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045390/ https://www.ncbi.nlm.nih.gov/pubmed/30023796 http://dx.doi.org/10.1021/acsomega.7b01932 |