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Self-Assembly Mechanism of a Peptide-Based Drug Delivery Vehicle

[Image: see text] We report the mechanism of the concentration-dependent self-assembly of a tetrapeptide. Peptide Boc-Trp-Leu-Trp-Leu-OMe self-assembles to form discrete nanospheres at a low concentration. Tryptophan side chains point outwards of the nanospheres while leucine side chains point towar...

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Detalles Bibliográficos
Autores principales: Pandit, Gopal, Roy, Karabi, Agarwal, Umang, Chatterjee, Sunanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045401/
https://www.ncbi.nlm.nih.gov/pubmed/30023862
http://dx.doi.org/10.1021/acsomega.7b01871