Cargando…

Structural Insight of Amyloidogenic Intermediates of Human Insulin

[Image: see text] Engaging Raman spectroscopy as a primary tool, we investigated the early events of insulin fibrilization and determined the structural content present in oligomer and protofibrils that are formed as intermediates in the fibril formation pathway. Insulin oligomer, as obtained upon i...

Descripción completa

Detalles Bibliográficos
Autores principales: Dolui, Sandip, Roy, Anupam, Pal, Uttam, Saha, Achintya, Maiti, Nakul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045404/
https://www.ncbi.nlm.nih.gov/pubmed/30023834
http://dx.doi.org/10.1021/acsomega.7b01776