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Structural Insight of Amyloidogenic Intermediates of Human Insulin
[Image: see text] Engaging Raman spectroscopy as a primary tool, we investigated the early events of insulin fibrilization and determined the structural content present in oligomer and protofibrils that are formed as intermediates in the fibril formation pathway. Insulin oligomer, as obtained upon i...
Autores principales: | Dolui, Sandip, Roy, Anupam, Pal, Uttam, Saha, Achintya, Maiti, Nakul C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045404/ https://www.ncbi.nlm.nih.gov/pubmed/30023834 http://dx.doi.org/10.1021/acsomega.7b01776 |
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