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S-Enantiomer of the Antitubercular Compound S006-830 Complements Activity of Frontline TB Drugs and Targets Biogenesis of Mycobacterium tuberculosis Cell Envelope

[Image: see text] A synthetic molecule S006-830, belonging to the class of thiophene-containing trisubstituted methanes, had shown good in vitro and in vivo bactericidal activity against drug-sensitive and drug-resistant Mycobacterium tuberculosis (Mtb). The molecule had also shown good druglike pha...

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Detalles Bibliográficos
Autores principales: Singh, Padam, Kumar, Shashi Kant, Maurya, Vineet Kumar, Mehta, Basant Kumar, Ahmad, Hafsa, Dwivedi, Anil Kumar, Chaturvedi, Vinita, Thakur, Tejender S., Sinha, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045410/
https://www.ncbi.nlm.nih.gov/pubmed/30023583
http://dx.doi.org/10.1021/acsomega.7b01281