Simultaneous Binding of Folic Acid and Methotrexate to Human Serum Albumin: Insights into the Structural Changes of Protein and the Location and Competitive Displacement of Drugs

[Image: see text] Protein structure can be flexible to adopt multiple conformations to house small molecules. In this paper, we have attempted to experimentally figure out how the structure of a transport protein steer the drug–drug competition (DDC) by maintaining the equilibrium distribution of th...

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Detalles Bibliográficos
Autores principales: Panja, Sudipta, Khatua, Deb Kumar, Halder, Mintu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045412/
https://www.ncbi.nlm.nih.gov/pubmed/30023775
http://dx.doi.org/10.1021/acsomega.7b01437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045412/
https://www.ncbi.nlm.nih.gov/pubmed/30023775
http://dx.doi.org/10.1021/acsomega.7b01437

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