Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation

[Image: see text] Synthetic DNA-binding inhibitors capable of gaining precise control over neurogenesis factors could obviate the current clinical barriers associated with the use of small molecules in regenerative medicine. Here, we report the design and bioefficacy of the synthetic ligand PIP-RBPJ...

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Detalles Bibliográficos
Autores principales: Wei, Yulei, Pandian, Ganesh N., Yu, Zutao, Zou, Tingting, Li, Yue, Darokar, Jayant, Hashiya, Kaori, Bando, Toshikazu, Sugiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045482/
https://www.ncbi.nlm.nih.gov/pubmed/30023873
http://dx.doi.org/10.1021/acsomega.8b00220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045482/
https://www.ncbi.nlm.nih.gov/pubmed/30023873
http://dx.doi.org/10.1021/acsomega.8b00220

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