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Targeting of a Photosensitizer to the Mitochondrion Enhances the Potency of Photodynamic Therapy

[Image: see text] Photodynamic therapy (PDT) involves use of a photosensitizer, whose activation with light leads to the production of singlet oxygen (SOS), generation of reactive oxygen species (ROS), and initiation of associated cell toxicity. Because a cell’s mitochondria constitute sites where o...

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Detalles Bibliográficos
Autores principales: Mahalingam, Sakkarapalayam M., Ordaz, Josue D., Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045488/
https://www.ncbi.nlm.nih.gov/pubmed/30023938
http://dx.doi.org/10.1021/acsomega.8b00692