SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts

During DNA synthesis, DNA replication and transcription machinery can collide, and the replication fork may temporarily dislodge RNA polymerase II (RNAPII) to resolve the transcription-replication conflict (TRC), a major source of endogenous DNA double-strand breaks (DSBs) and common fragile site (C...

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Detalles Bibliográficos
Autores principales: Li, Min, Xu, Xiaohua, Chang, Chou-Wei, Zheng, Li, Shen, Binghui, Liu, Yilun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045570/
https://www.ncbi.nlm.nih.gov/pubmed/30006506
http://dx.doi.org/10.1038/s41467-018-05236-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045570/
https://www.ncbi.nlm.nih.gov/pubmed/30006506
http://dx.doi.org/10.1038/s41467-018-05236-y

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