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Down-regulation of vascular GLP-1 receptor expression in human subjects with obesity

It has been thought that incretin signaling prevents arteriosclerosis, and very recently anti-arteriosclerotic effects through GLP-1 receptor were finally demonstrated in clinical human study. The purpose of this study was to investigate how vascular GLP-1 receptor expression is influenced in human...

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Detalles Bibliográficos
Autores principales: Kimura, Tomohiko, Obata, Atsushi, Shimoda, Masashi, Shimizu, Ikki, da Silva Xavier, Gabriela, Okauchi, Seizo, Hirukawa, Hidenori, Kohara, Kenji, Mune, Tomoatsu, Moriuchi, Saeko, Hiraoka, Arudo, Tamura, Kentaro, Chikazawa, Genta, Ishida, Atsuhisa, Yoshitaka, Hidenori, Rutter, Guy A., Kaku, Kohei, Kaneto, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045606/
https://www.ncbi.nlm.nih.gov/pubmed/30006590
http://dx.doi.org/10.1038/s41598-018-28849-1