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ACGH detects distinct genomic alterations of primary intrahepatic cholangiocarcinomas and matched lymph node metastases and identifies a poor prognosis subclass

Lymph node metastases (LNM) are an important prognostic factor for patients with intrahepatic cholangiocarcinoma, but underlying genetic alterations are poorly understood. Whole genome array comparative genomic hybridization (aCGH) was performed in 37 tumors and 14 matched LNM. Genomic analyses of t...

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Detalles Bibliográficos
Autores principales: Jansen, Ruben, Moehlendick, Birte, Bartenhagen, Christoph, Tóth, Csaba, Lehwald, Nadja, Stoecklein, Nikolas H., Knoefel, Wolfram T., Lachenmayer, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045619/
https://www.ncbi.nlm.nih.gov/pubmed/30006612
http://dx.doi.org/10.1038/s41598-018-28941-6