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ACGH detects distinct genomic alterations of primary intrahepatic cholangiocarcinomas and matched lymph node metastases and identifies a poor prognosis subclass
Lymph node metastases (LNM) are an important prognostic factor for patients with intrahepatic cholangiocarcinoma, but underlying genetic alterations are poorly understood. Whole genome array comparative genomic hybridization (aCGH) was performed in 37 tumors and 14 matched LNM. Genomic analyses of t...
Autores principales: | Jansen, Ruben, Moehlendick, Birte, Bartenhagen, Christoph, Tóth, Csaba, Lehwald, Nadja, Stoecklein, Nikolas H., Knoefel, Wolfram T., Lachenmayer, Anja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045619/ https://www.ncbi.nlm.nih.gov/pubmed/30006612 http://dx.doi.org/10.1038/s41598-018-28941-6 |
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