Codon usage clusters correlation: towards protein solubility prediction in heterologous expression systems in E. coli

Production of soluble recombinant proteins is crucial to the development of industry and basic research. However, the aggregation due to the incorrect folding of the nascent polypeptides is still a mayor bottleneck. Understanding the factors governing protein solubility is important to grasp the und...

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Detalles Bibliográficos
Autores principales: Pellizza, Leonardo, Smal, Clara, Rodrigo, Guido, Arán, Martín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045634/
https://www.ncbi.nlm.nih.gov/pubmed/30006617
http://dx.doi.org/10.1038/s41598-018-29035-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045634/
https://www.ncbi.nlm.nih.gov/pubmed/30006617
http://dx.doi.org/10.1038/s41598-018-29035-z

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