Cargando…
Codon usage clusters correlation: towards protein solubility prediction in heterologous expression systems in E. coli
Production of soluble recombinant proteins is crucial to the development of industry and basic research. However, the aggregation due to the incorrect folding of the nascent polypeptides is still a mayor bottleneck. Understanding the factors governing protein solubility is important to grasp the und...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045634/ https://www.ncbi.nlm.nih.gov/pubmed/30006617 http://dx.doi.org/10.1038/s41598-018-29035-z |