Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis

Myocardial infarction (MI) is a major cause of death in Western countries and finding new strategies for its prevention and treatment is thus of high priority. In a previous study, we have demonstrated a pathophysiologic relevance for the heterophilic interaction of CCL5 and CXCL4 in the progression...

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Detalles Bibliográficos
Autores principales: Vajen, Tanja, Koenen, Rory R., Werner, Isabella, Staudt, Mareike, Projahn, Delia, Curaj, Adelina, Sönmez, Tolga Taha, Simsekyilmaz, Sakine, Schumacher, David, Möllmann, Julia, Hackeng, Tilman M., Hundelshausen, Philipp von, Weber, Christian, Liehn, Elisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045661/
https://www.ncbi.nlm.nih.gov/pubmed/30006564
http://dx.doi.org/10.1038/s41598-018-29026-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045661/
https://www.ncbi.nlm.nih.gov/pubmed/30006564
http://dx.doi.org/10.1038/s41598-018-29026-0

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