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Pyruvate carboxylase supports the pulmonary tropism of metastatic breast cancer

BACKGROUND: Overcoming systemic dormancy and initiating secondary tumor grow under unique microenvironmental conditions is a major rate-limiting step in metastatic progression. Disseminated tumor cells encounter major changes in nutrient supplies and oxidative stresses compared to the primary tumor...

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Detalles Bibliográficos
Autores principales: Shinde, Aparna, Wilmanski, Tomasz, Chen, Hao, Teegarden, Dorothy, Wendt, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045837/
https://www.ncbi.nlm.nih.gov/pubmed/30005601
http://dx.doi.org/10.1186/s13058-018-1008-9