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Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes
BACKGROUND: Alternative polyadenylation (APA) results in messenger RNA molecules with different 3′ untranslated regions (3’ UTRs), affecting the molecules’ stability, localization, and translation. APA is pervasive and implicated in cancer. Earlier reports on APA focused on 3’ UTR length modificatio...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045855/ https://www.ncbi.nlm.nih.gov/pubmed/30005633 http://dx.doi.org/10.1186/s12864-018-4903-7 |