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Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes

BACKGROUND: Alternative polyadenylation (APA) results in messenger RNA molecules with different 3′ untranslated regions (3’ UTRs), affecting the molecules’ stability, localization, and translation. APA is pervasive and implicated in cancer. Earlier reports on APA focused on 3’ UTR length modificatio...

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Detalles Bibliográficos
Autores principales: Xue, Zhuyi, Warren, René L., Gibb, Ewan A., MacMillan, Daniel, Wong, Johnathan, Chiu, Readman, Hammond, S. Austin, Yang, Chen, Nip, Ka Ming, Ennis, Catherine A., Hahn, Abigail, Reynolds, Sheila, Birol, Inanc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045855/
https://www.ncbi.nlm.nih.gov/pubmed/30005633
http://dx.doi.org/10.1186/s12864-018-4903-7