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Comparison of immunological characteristics between paired mismatch repair-proficient and -deficient colorectal cancer patients
BACKGROUND: Currently, mismatch repair-deficient (dMMR) status is a promising candidate for targeted immune checkpoint inhibition therapy in colorectal cancer (CRC) patients, however, the potential immunological mechanism has not yet been well clarified and some other predictors need to be excavated...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045865/ https://www.ncbi.nlm.nih.gov/pubmed/30005666 http://dx.doi.org/10.1186/s12967-018-1570-z |