Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease

One of the earliest pathological features characterizing Alzheimer’s disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating this loss of neuronal connectivity, the contribution of Rho-GTPases is of particular interest. This family of proteins has been known for ye...

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Detalles Bibliográficos
Autores principales: Borin, Mirta, Saraceno, Claudia, Catania, Marcella, Lorenzetto, Erika, Pontelli, Valeria, Paterlini, Anna, Fostinelli, Silvia, Avesani, Anna, Di Fede, Giuseppe, Zanusso, Gianluigi, Benussi, Luisa, Binetti, Giuliano, Zorzan, Simone, Ghidoni, Roberta, Buffelli, Mario, Bolognin, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045891/
https://www.ncbi.nlm.nih.gov/pubmed/30005699
http://dx.doi.org/10.1186/s40478-018-0567-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045891/
https://www.ncbi.nlm.nih.gov/pubmed/30005699
http://dx.doi.org/10.1186/s40478-018-0567-4

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