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Lead Induces Genotoxicity via Oxidative Stress and Promoter Methylation of DNA Repair Genes in Human Lymphoblastoid TK6 Cells

BACKGROUND: Lead (Pb) is a widely used metal in modern industry and is regarded as a health hazard. Although lead-induced genotoxicity has been confirmed, the direct evidence that lead induces genotoxicity in human cells and its related mechanisms has not been fully elucidated. In this study, for th...

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Detalles Bibliográficos
Autores principales: Liu, Xiangquan, Wu, Jingying, Shi, Wenyan, Shi, Wenhua, Liu, Hekun, Wu, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045917/
https://www.ncbi.nlm.nih.gov/pubmed/29933360
http://dx.doi.org/10.12659/MSM.908425