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Therapeutic landscape in mutational triple negative breast cancer

Triple negative breast cancer (TNBC) is a heterogeneous disease with aggressive behavior and poor prognosis. Genomic sequencing has detected a distinctive mutational portrait of both the germline and somatic alterations in TNBC, which is staggeringly different from other breast cancer subtypes. The...

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Detalles Bibliográficos
Autores principales: Shi, Yaqin, Jin, Juan, Ji, Wenfei, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046102/
https://www.ncbi.nlm.nih.gov/pubmed/30007403
http://dx.doi.org/10.1186/s12943-018-0850-9